Synopsis

The story of how one company triggered the worst drug epidemic in American history. Look into the epicenter of America's struggle with opioid addiction, from a distressed Virginia mining community, to the hallways of the DEA, and to the opulence of "one percenter" Big Pharma Manhattan.

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Michael Keaton

as Samuel Finnix

Peter Sarsgaard

as Rick Mountcastle

Michael Stuhlbarg

as Richard Sackler

Will Poulter

as Billy Cutler

John Hoogenakker

as Randy Ramseyer

Kaitlyn Dever

as Betsy Mallum

Rosario Dawson

as Bridget Meyer

Will Chase

as Michael Friedman

Cleopatra Coleman

as Grace Pell

Parker Sack

as Dirk

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